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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461373 / VAT: CZ60461373

Czech Post certified digital mail code: sp4j9ch

Copyright: UCT Prague
Information provided by the Department of International Relations and the Department of R&D. Technical support by the Computing Centre. [paticka_odkaz_mail] => mailto:info@vscht.cz [zobraz_desktop_verzi] => [more_info] => [drobecky] => You are here: UCT PragueWeb PhD [aktualizovano] => Updated [autor] => Author [zobraz_mobilni_verzi] => [social_li_odkaz] => [dokumenty_kod] => [dokumenty_nazev] => [dokumenty_platne_od] => [dokumenty_platne_do] => [nepodporovany_prohlizec] => [den_kratky_6] => [novinky_kategorie_1] => [novinky_kategorie_2] => [novinky_kategorie_3] => [novinky_kategorie_4] => [novinky_kategorie_5] => [novinky_archiv_url] => [novinky_servis_archiv_rok] => [novinky_servis_nadpis] => [novinky_dalsi] => [den_kratky_2] => [archiv_novinek] => [cookie-policy-title] => Cookies settings [cookie-policy-info] =>

We value your privacy

This website store cookies which are necessary for the proper function of this website (strictly necessary) in your browser. With your consent, the website will also use and store in your browser other cookies for the purpose of anonymous analysis of website traffic (analytical) and for the personalization of advertising (marketing). You can withdraw or modify your consent at any time by opening the "Cookies settings" menu at the bottom of the website. You provide your consent to UCT Prague for the domain vscht.cz including 3rd level domains. Further information can be found on the Privacy Policy and Cookie Policy pages. [cookie-policy-necessary] => Necessary [cookie-policy-necessary-text] => These cookies are necessary for the website to function properly and therefore cannot be disabled. [cookie-policy-analytics] => Analytical [cookie-policy-analytics-text] => We use web analytics cookies to anonymously analyse website visits and usage. [cookie-policy-functional] => Functional [cookie-policy-functional-text] => [cookie-policy-button-accept-all] => Accept all [cookie-choose-handler] => Custom settings [cookie-choose-handler-send] => Save custom settings [cookie-reject-all-handler] => Accept only the necessary [cookie-policy-button-customize] => Cookies settings [cookie-policy-marketing] => Marketing [cookie-policy-marketing-text] => These cookies are used to evaluate advertising campaigns and personalize ads. [kalendar_nadpis] => Calendar [cely_kalendar] => All events ) [poduzel] => stdClass Object ( [50384] => stdClass Object ( [obsah] => [poduzel] => stdClass Object ( [50385] => stdClass Object ( [obsah] => [iduzel] => 50385 [canonical_url] => _clone_ [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) [50388] => stdClass Object ( [obsah] => [iduzel] => 50388 [canonical_url] => _clone_ [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) [50389] => stdClass Object ( [obsah] => [iduzel] => 50389 [canonical_url] => _clone_ [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) ) [iduzel] => 50384 [canonical_url] => _clone_ [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) [58015] => stdClass Object ( [obsah] => [poduzel] => stdClass Object ( [58016] => stdClass Object ( [nazev] => [seo_title] => PhD studies at UCT Prague [seo_desc] => [autor] => [autor_email] => [obsah] => [urlnadstranka] => [ogobrazek] => [pozadi] => [iduzel] => 58016 [canonical_url] => [skupina_www] => Array ( ) [url] => /home [sablona] => stdClass Object ( [class] => boxy [html] => [css] => [js] => $(function() { setInterval(function () { $('*[data-countdown]').each(function() { CountDownIt('#'+$(this).attr("id")); }); },1000); setInterval(function () { $('.homebox_slider:not(.stop)').each(function () { slide($(this),true); }); },5000); }); function CountDownIt(selector) { var el=$(selector);foo = new Date; var unixtime = el.attr('data-countdown')*1-parseInt(foo.getTime() / 1000); if(unixtime<0) unixtime=0; var dnu = 1*parseInt(unixtime / (3600*24)); unixtime=unixtime-(dnu*(3600*24)); var hodin = 1*parseInt(unixtime / (3600)); unixtime=unixtime-(hodin*(3600)); var minut = 1*parseInt(unixtime / (60)); unixtime=unixtime-(minut*(60)); if(unixtime<10) {unixtime='0'+unixtime;} if(dnu<10) {unixtime='0'+dnu;} if(hodin<10) {unixtime='0'+hodin;} if(minut<10) {unixtime='0'+minut;} el.html(dnu+':'+hodin+':'+minut+':'+unixtime); } function slide(el,vlevo) { if(el.length<1) return false; var leva=el.find('.content').position().left; var sirka=el.width(); var pocet=el.find('.content .homebox').length-1; var cislo=leva/sirka*-1; if(vlevo) { if(cislo+1>pocet) cislo=0; else cislo++; } else { if(cislo==0) cislo=pocet-1; else cislo--; } el.find('.content').animate({'left':-1*cislo*sirka}); el.find('.slider_puntiky a').removeClass('selected'); el.find('.slider_puntiky a.puntik'+cislo).addClass('selected'); return false; } function slideTo(el,cislo) { if(el.length<1) return false; var sirka=el.width(); var pocet=el.find('.content .homebox').length-1; if(cislo<0 || cislo>pocet) return false; el.find('.content').animate({'left':-1*cislo*sirka}); el.find('.slider_puntiky a').removeClass('selected'); el.find('.slider_puntiky a.puntik'+cislo).addClass('selected'); return false; } [autonomni] => 1 ) ) [75749] => stdClass Object ( [nazev] => Onboarding [seo_title] => Onboarding [seo_desc] => [autor] => [autor_email] => [obsah] =>

What is onboarding?

Onboarding is a key process of integrating new employees into the organisation, thereby enhancing both their professional, social, cultural and organisational integration. As a result, employees feel welcomed as part of the organisation and better prepared for the tasks ahead of them. The sooner the new employee feels welcome and fully informed, the better and quicker they will be able to contribute to the organisation successfully.

Onboarding procedures are common in the private sector but often absent in academic institutions. In particular for newly hired Early Career Researchers (ECR), namely PhD candidates, such procedures will strongly impact both their integration into the organisation and clarification of roles and responsibilities of all stakeholders involved in their programme. In order to maximize their impact, it is therefore important that onboarding procedures are approved and supported by supervisors and Postgraduate offices. While it has been shown that successful onboarding contributes to increased well-being and motivation, many ECRs often feel somewhat lost and poorly supported when entering academia, leading to doubt, insecurity and sometimes even an early abandonment of their research project.

UCT and onboarding

In collaboration with the PRIDE network (Professionals in Doctoral Education), a working group was formed with the aim of drafting a publication on onboarding, focusing for the first time on doctoral candidates and postdocs and their adaptation process at the university.

UCT Prague initially launched an extensive questionnaire to assess awareness of onboarding, whether and how many people have encountered it, and what they would welcome within the academic environment. After evaluating the questionnaire, meetings were held in the private sector with HR professionals. We wanted to verify how onboarding is conducted in private companies and how we can leverage their know-how and experiences in our context.

The collected materials and interviews with HR professionals were used to create an adaptation plan, which was piloted from September 2023 at three institutes of  UCT Prague. The resulting adaptation plan, which is part of this page, will serve the needs of UCT Prague supervisors who work with newly hired doctoral candidates. Furthermore, the adaptation plan will be utilized for the PRIDE network publication, serving as a foundation for other European universities.

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Zde se zobrazují boxy (ze složky phd-boxy)

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UCT Prague cooperates with partner universities in Europe on joint doctoral study programmes.

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What is a “Double-Degree” programme?

It is doctoral study programme that is leading to two diplomas from both home university as well as partner university. Student works on one dissertation, the study programmes are fully integrated between collaborating universities and include specialized courses at home university and one interdisciplinary at partner university. 

Each successful applicant signs individual contract about doctoral double degree based on his/her particular situation (research area, supervisor’s requirements, home university requirements etc.). The contract is signed between UCT Prague and student’s home university.

Requirements for doctoral double degree contract:

  • Student has to agree with two supervisors – one from the home university, one from UCT Prague
  • Student has to be accepted by his/her supervisor to PhD studies at UCT Prague
  • Student has to be accepted to PhD studies at his/her home university
  • UCT Prague and student’s home university have to have a joint double degree study programme (list of offered programmes below)

Contact persons at UCT Prague

First contact (study matter) - Contact person of each double degree study programme.

Second contact (general matter, information about the application proceedings)– Department of International Relations: international@vscht.cz

Finances

In terms of cooperation with partner universities no tuition is required. Students are expected to cover any additional costs themselves.

What are the advantages?

Besides improved employability of graduates, there is emphasis on research activity coupled with a possibility to lead small research groups. The program inherently strengthens professional language knowledge. There are possibilities to gain practical skills thanks to cooperation with partner companies such as Zentiva, Zeva, Contipro, Lonza Biotec or in practically oriented departments of Czech Academy of Sciences, where are practical traineeships available. Last but not least there is excellent support of students, including motivational scholarships.

Double degree programmes offered

There are 8 programmes at 4 faculties

FCT – Faculty of Chemical Technology

FET – Faculty of Environmental Technology

FBT – Faculty of Food and Biochemical Technology

FCE – Faculty of Chemical Engineering

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Bioinformatics

Bioinformatics

Doctoral Programme, Faculty of Chemical Technology

The aim of the DSP programme is to educate specialists in bioinformatics, which is a combination of molecular and cell biology, biochemistry, statistics and computer science. Bioinformatics deals with the development of tools for the management of biological databases, algorithms for the processing of molecular-biological data and methods for the analysis and interpretation of relationships in these data. Most of the projects are biologically oriented with the aim to understand the complex context in the studied biological phenomena. However, we also run IT-oriented topics that include the development of algorithms or data processing methods.

Careers

The combination of the education in natural sciences and informatics qualifies graduates to work in interdisciplinary teams. Graduates will find employment in a wide range of areas where data obtained by instrumental analysis of biological samples are processed. Graduates can also rely on a broad knowledge of informatics and can be successful in the development of software technologies, especially for data analytics. Graduates will further find employment in scientific infrastructures built in the Czech Republic within the framework of European operational programs. Due to the persisting lack of experts with an interdisciplinary education, graduates will also be easily employable outside the Czech Republic. Typical positions that DSP Bioinformatics graduate can hold: - researcher in basic or applied research in the public or private sector in the fields of biomedicine, clinical medicine, medical and pharmaceutical chemistry, food, agriculture, biotechnology or forensic science. Typical positions are postdoc, programmer, research associate, research fellow, project leader, project manager. - university lecturer in bioinformatics, computational biology, computational chemistry or applied informatics. Typical positions are assistant professor, assistant, lecturer. - software developer or data analyst in IT companies. - professional positions that require organizational and analytical skills and expertise not only in bioinformatics. Typical job positions include state administration at the highest management levels, organizations that are methodologically and organizationally engaged in science and research or non-profit and educational organizations.

Programme Details

Study Language English
Standard study length 4 years
Form of study combined , full-time
Guarantor
Place of study Praha
Capacity 8 students
Programme code (national) P0588D030010
Programme Code (internal) AD107
Number of Ph.D. topics 5

Ph.D. topics for study year 2024/25

Machine learning in biochemistry

Granting Departments: Department of Organic Chemistry
Institute of Organic Chemistry and Biochemistry of the CAS, v. v. i.
Supervisor: Mgr. Tomáš Pluskal, Ph.D.

Annotation


Our lab combines cutting-edge experimental (e.g., LC-MS, metabolomics, RNA-seq) and computational (e.g., bioinformatics, molecular networking, machine learning) approaches to develop rapid, generally applicable workflows for the discovery and utilization of bioactive molecules derived from plants. The successful candidate for this position will be developing machine learning models for the prediction of enzymatic activities of enzymes in specialized biosynthetic pathways.
Contact supervisor Study place: Institute of Organic Chemistry and Biochemistry of the CAS, v. v. i.

Drug discovery with explainable artificial intelligence

Granting Departments: Department of Informatics and Chemistry
Supervisor: Ing. Martin Šícho, Ph.D.

Annotation


The PhD project focuses on the application of explainable artificial intelligence (XAI) in the field of computer-aided drug design. It aims to develop new methodologies that make the decision-making processes of AI models in drug discovery more transparent and understandable. The project will explore how XAI can improve the reliability of predictive models used for identifying potential drug candidates. A significant aspect of the research will involve integrating XAI approaches with existing drug design algorithms to enhance their interpretability. Ultimately, this project seeks to bridge the gap between advanced AI techniques and practical pharmaceutical applications, fostering more efficient and informed drug development.
Contact supervisor Study place: Department of Informatics and Chemistry, FCT, VŠCHT Praha

Molecular mechanisms of the environmental stress response in model cell systems

Granting Departments: Department of Informatics and Chemistry
Institute of Experimental Medicine AS CR, v.v.i.
Supervisor: RNDr. Pavel Rössner, Ph.D.

Annotation


Environmental pollution represents a global problem affecting health of most of the population worldwide. To effectively protect the organism against negative impacts of environmental pollution detail molecular mechanisms of effects of pollutants need to be revealed. The aim of the thesis is to evaluate the impact of air pollution of whole-genome mRNA expression and epigenetic mechanisms (miRNA expression, DNA methylation) in model human cell systems in vitro. Lung and olfactory mucosa tissue models will be exposed to ambient air in localities with different levels of environmental pollution and mRNA expression profiles and epigenetic changes will be evaluated. The thesis should contribute to formulation of a detailed model describing, at molecular level, the response of the organism to ambient air pollutants.
Contact supervisor Study place: Institute of Experimental Medicine AS CR, v.v.i.

Ancient DNA population genomics: detection of population substructure in human populations

Granting Departments: Department of Informatics and Chemistry
Institute of Molecular Genetics of the CAS, v. v. i.
Supervisor: RNDr. Edvard Ehler, Ph.D.

Annotation


The development of ancient DNA (aDNA) technologies in recent years gave rise of vast number of human genomic samples, especially from the prehistorical Europe. Most of the known samples are coming from the first four millennia before CE, a periods described as Neolithic, Bronze Age and Iron Age epochs based on associated archaeological findings. These populations are described primarily using their cultural features (archaeological findings, e.g., pottery, burials, food production, technology). The biological relationship between different populations living at that time are only beginning to be unfolded. The applicant will assist in bioinformatic processing of aDNA genomic samples (within an awarded CZ-PL Weave international grant project), focusing on populations from Bronze and Iron Age period from central Europe. The obtained genomic data will be utilized in the main goal of the proposed PhD project – to test different methods of detection of the population substructure and similarities, and identification of population admixture or isolation events. The applicant will be encouraged to test various population genetics methods, as well as modern dimensionality reduction and machine-learning techniques and approaches to describe and comprehend the genomic data on population level. This should allow us to better recognize the genetic background of the target populations, estimate the gene flow between them and thus the regional variability, and help us ascertain their social structure, marriage patterns and identify possible migrations.
Contact supervisor Study place: Institute of Molecular Genetics of the CAS, v. v. i.

Advancing Drug Design with Artificial Intelligence and Nuclear Magnetic Resonance

Granting Departments: Department of Informatics and Chemistry
Supervisor: prof. Mgr. Daniel Svozil, Ph.D.

Annotation


In this industrial PhD project, the candidate will join a dynamic team at the intersection of Cheminformatics, Artificial Intelligence, and NMR, focusing on Drug Design. The role involves enhancing AI|ffinity's NMR-AI platform components for virtual screening, hit discovery, and lead optimization. This task includes developing innovative software solutions for one or more of the following applications: 1. Enhancing 2D molecular representations to bolster the accuracy of ligand-based virtual screening, utilizing 1D NMR screening spectra. 2. Improving AI-driven, structure-based lead optimization algorithms, harnessing the power of 1D NMR restraints. 3. Innovating in de novo drug design algorithms by leveraging ligand epitope information from 1D NMR screening experiments. The project offers practical application of these tools in real-world drug discovery, in collaboration with AI|ffinity and its partners, and includes an international industrial internship for global exposure and insights, directly contributing to drug development.
Contact supervisor Study place: Department of Informatics and Chemistry, FCT, VŠCHT Praha
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